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Aspirin plus dipyridamole more effective for TIA

Aspirin plus dipyridamole is more effective for secondary prevention of a TIA or ischaemic stroke than aspirin alone, according to an updated meta-analysis.

European researchers analysed data from 7,612 patients in five trials including the recently published ESPIRIT study and found treatment overall reduced the risk of vascular death, non-fatal heart attack and non-fatal stroke by 18%.

But combination treatment was more effective than aspirin alone in preventing recurrent stroke with a hazard ratio of 0.78.

J Neurol Neurosurg Psychiatry 2008 6 October early online publication

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