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Bicarbonate 'may slow chronic kidney disease'

Dietary supplementation with bicarbonate may slow the progression of chronic kidney disease, according to a study by UK researchers.

A team at St Barts and the London hospital randomly assigned 134 adults with CKD stage four to either supplementation with oral sodium bicarbonate or standard care for two years.

Creatinine clearance rates declined more slowly with bicarbonate supplementation, reaching 5.93 ml/min per 1.73m2 compared with 1.88 ml/min per 1.73m2 in the control group.

Patients supplemented with bicarbonate were 15% less likely to experience rapid disease progression than controls.

Journal of the American Society of Nephrology 2009, 16 July early online publication

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