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Clinical quiz - identify these drug reactions

Are these statements true or false? Find the answers by clicking on the link at the bottom.

Are these statements true or false? Find the answers by clicking on the link at the bottom.

1. A rash resulting from the use of amoxicillin in a patient with glandular fever

• A similar rash can occur when any antibiotic is used in a patient with this condition

• Means that the patient should avoid this antibiotic in the future

• Is mild and non-irritant

• Is usually urticarial

• Affects 80-90% of patients erroneously given this antibiotic in this situation

2. Erythema multiforme

• When caused by drugs, the culprits are commonly aspirin or sulphonamides

• If associated with mouth, genital and ocular ulceration, with fever, is known as Stevens-Johnson syndrome

• Most patients are 40 or older

• Is characterised by ‘target lesions'

• Usually resolves in two or three weeks

3. Aspirin sensitivity

• In this case is causing giant urticaria

• May also result in angio-oedema, asthma, rhinitis, anaphylaxis and photodermatitis

• Occurs in about 10% of asthmatic adults

• Is part of Samter's triad

• In an individual puts them at high risk of reactions to other NSAIDs

4. A drug rash caused by an ACE inhibitor

• Occurs in about 1% of patients taking these drugs

• Is more likely to be caused by captopril than other

ACE inhibitors

• Is usually a non-pruritic, maculopapular rash

• Can be photosensitive

• Is likely to recur if the patient is switched to an ARB

Drug reactions Picture 1 Pic 4 - What is this drug reaction? Pic 3 2 Answers

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