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Depression increases Alzheimer's risk

People who have had depression are more likely to develop Alzheimer's disease than those who have not, Dutch research suggests.

In a six-year follow-up of 486 people aged 60 to 90 who did not have dementia, 134 had had at least one episode of depression for which they sought advice.

Over the study period, people who had experienced depression were 2.5 times more likely to develop Alzheimer's disease than people who had never had depression. Those who had depression before age

60 were nearly four times more likely to develop Alzheimer's than those who did not.

Neurology 2008;70:1258-64

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