Framingham underestimates the risk of CHD in diabetics
The established method of assessing cardiovascular risk in people with type 2 diabetes is seriously underestimating both risk and costs to the NHS, two new studies suggest.
UK research presented to the conference found the Framingham method underestimates risk in diabetics compared with the UK prospective diabetes study (UKPDS).
The Framingham charts remain the gold standard in risk estimation even though only 6 per cent of subjects in the Framingham heart study were diabetics.
The first new study, based in Warwickshire and Birmingham, found the UKPDS would reclassify 35.4 per cent of patients classified by Framingham as below the 15 per cent risk threshold for treatment.
And a Cardiff study found the UKPDS predicted 72 per cent more coronary heart disease events and 143 per cent more strokes than Framingham.
Researchers concluded that 'type 2 diabetes models driven by Framingham may be unreliable'.