GPs defy gloomy forecast on CHD and BP points
GPs are bracing themselves for a new wave of patients alarmed over SSRIs after new research in this week's BMJ failed to rule out a link with suicide.
In one study, researchers analysed 702 trials of 87,000 patients and found those taking SSRIs were 2.28 times as likely to attempt suicide as those on placebo. There was no increase in risk of fatal suicides compared with placebo and no difference between
SSRIs and tricyclic antidepressants in risk of suicide attempt.
Two further studies found no evidence SSRIs increased the risk of suicide although one found weak evidence of increased risk of self-harm in under-18s.
The Medicines and Healthcare Products Regulatory Agency said it had included the studies in its December review and that GPs should still follow its recommendations.