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At the heart of general practice since 1960

GPs resistant over smoking advice

Are the days numbered for use of ß-blockers in hypertension?

2004 December

Blood pressure arm of ASCOT trial stopped a year early after finding an ACE inhibitor plus calcium channel blocker had ‘substantial benefits' over a

ß-blocker and diuretic

December

LIFE trial of more than 9,000 patients found risk of dying from stroke was 35 per cent lower with an ARB than a ß-blocker

2005 March

More results from the ASCOT trial are unveiled at the American College of Cardiology meeting in Orlando showing that an ACE inhibitor and calcium channel blocker could cut all-cause mortality by 15 per cent compared with a diuretic and ß-blocker; NICE and BHS announce they are to hold a high-level meeting to issue new guidance when results are published

September

Formal release of ASCOT data prompts NICE to announce it will review its guidance in light of the data

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