Intense cholesterol and BP therapy no better
Aggressive treatment of hypertension and raised cholesterol in high-risk patients is no better than standard treatment for reducing cardiovascular events, a US study finds.
The research assessed 499 patients with type 2 diabetes, raised LDL cholesterol and high blood pressure, but with no history of cardiovascular events.
Mean carotid IMT progressed slightly with standard treatment and regressed in the intensive treatment group.
But there were only eight primary cardiovascular events in the standard treatment group and 11 in the intensive treatment group – with no significant difference between the two.
JAMA 2008 299:1678-89