Intensive lipid lowering slows atherosclerosis
Intensive lipid lowering reduces the progression of atherosclerosis, even in those who would not normally be considered for statin treatment.
A randomised Dutch study looked at the effect of rosuvastatin 40 mg treatment on carotid intima media thickness compared with placebo in 984 low-risk participants.
They found a significant difference in atherosclerosis progression between the groups after one year, with an increase of 0.0032mm in the rosuvastatin group and 0.0133mm in the placebo group.
J Intern Med 2009; 28 February early online