Low dose statins remove heart risk in FH patients
Relatively low doses of statins can almost completely remove the excess heart attack risk of patients with familial hypercholesterolaemia, say Dutch researchers.
Their cohort study followed 2,146 FH patients receiving statin therapy for over eight years, with the vast majority taking simvastatin at a mean dose of 33g.
Despite the low statin dose, the researchers found a ‘pronounced' 80% reduction in the risk of coronary heart disease in this population, with their risk of heart attack approaching that of the general population by the end of the study.
BMJ 2008 11 November early online publicationSimvastatin - low doses of statins almost competely remove heart risk in FH patients