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Metformin may protect against pancreatic cancer

Prescribing metformin to patients with type 2 diabetes offers some protection against pancreatic cancer, suggests data from a US study.

The hospital-based case-control study from 2004 to 2008 looked at 973 patients with pancreatic adenocarcinoma. Researchers found patients with diabetes who had taken metformin had a significantly lower risk of pancreatic cancer compared to those who had not.

Patients on metformin had a 62% lower risk of pancreatic cancer. However those who had taken insulin had a significantly higher risk of pancreatic cancer compared to those who had not.

Gastroenterology August 2009;137(2):482-488

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