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Miscarriage infection risk is low for all management treatments

A study of the incidence of gynaecological infection after miscarriage during the first trimester has concluded that the risk of infection is low with either surgical, expectant or medical management, according to research published in the BMJ.

The randomised, controlled trial examined 1200 women of less than

13 weeks' gestation with early fetal demise or incomplete miscarriage from seven UK hospitals – 399 undertook expectant management, 398 medical management and 403 had surgical management.

Researchers found that there were no differences in the incidence of confirmed infection within 14 days between the expectant or surgical group (risk difference was 0.2 per cent); or between the medical and the surgical group (risk difference was 0.7 per cent).

However the UK researchers found that there were a greater number of unplanned hospital admissions and surgical curettage after expectant and medical management compared with surgical management.


Trinder J, Brocklehurst P et al. Management of miscarriage: expectant, medical, or surgical? Results

of randomised controlled trial (miscarriage treatment (MIST) trial). BMJ 2006;332:1235–40

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