This site is intended for health professionals only

At the heart of general practice since 1960

Missed bisphosphonate dose raises fracture risk

Elderly women who take less than 80% of their prescribed doses of alendronate or risedronate have a 27% increased risk of nonvertebral fractures, say Canadian researchers.

A case-control study of more than 30,000 women, set up to assess the implications of non-compliance, analysed non-vertebral fractures which occurred a year after starting therapy.

The risk was highest in women aged over 80. In these women, only taking eight in ten doses or less raised the risk of a nonvertebral fracture by 48%.

Rate this article 

Click to rate

  • 1 star out of 5
  • 2 stars out of 5
  • 3 stars out of 5
  • 4 stars out of 5
  • 5 stars out of 5

0 out of 5 stars

Have your say