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Osteoporosis drug cuts vertebral fractures in over-50s

Strontium ranelate can reduce the risk of vertebral fracture in young postmenopausal women, a European study suggests.

The Spinal Osteoporosis Therapeutic Intervention study, in 353 postmenopausal women aged 50-65 with severe osteoporosis, randomised patients to strontium ranelate 2g a day or placebo.

Over four years of follow-up, strontium ranelate reduced the risk of vertebral fracture by 35% and increased bone mineral density from baseline by 15.8% at the lumbar spine and 7.1% at the femoral neck.

Ann Rheum Dis 2008;67:1736-8

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