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Paper of the Day - Lowering BP has no effect on dementia risk

There is no evidence that lowering blood pressure prevents cognitive impairment or dementia in patients with no history of cerebrovascular disease.

Researchers at Queen's University Belfast have reviewed data from three trials involving 12,091 patients with hypertension where follow up data on cognitive function was available.

There was no difference in the incidence of dementia in patients treated with an antihypertensive compared to placebo. Two of the trials also had data on mini mental state examination scores but there was no difference between treatment and placebo.

There was no convincing evidence from the trials identified that BP lowering prevents the development of dementia or cognitive impairment in hypertensive patients with no apparent prior cerebrovascular disease, the authors conclude.

J Neurol Neurosurg Psychiatry 2008; 789:4-5.

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