This site is intended for health professionals only

At the heart of general practice since 1960

pulse june2020 80x101px
Read the latest issue online

GPs go forth

Paper of the day - switch to glargine improves diabetes control

Switching Type 2 diabetes patients poorly controlled on pre-mixed insulins to glargine significantly improves glycaemic control, say UK researchers.

The safety and efficacy of switching from premixed insulin to the insulin analogue was studied in 686 patients with inadequately controlled diabetes. Twenty-four weeks after switching, average HbA1cs had dropped from 9.0 to 8.0 (p<0.001) and fasting blood glucose levels from 9.27 to 5.93 mmol/l (p,0.001). Adding prandial glucose further improved control. The authors say better control was gained with a low risk of severe hypoglycaemic episodes.

Diabetes Res Clin Pract online 5 November

Rate this article 

Click to rate

  • 1 star out of 5
  • 2 stars out of 5
  • 3 stars out of 5
  • 4 stars out of 5
  • 5 stars out of 5

0 out of 5 stars

Have your say