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Pulse and BP link to coronary artery calcium

Pulse pressure and systolic blood pressure are strong indicators of coronary artery calcium in postmenopausal women, but there is an inverse relationship with diastolic blood pressure, analysis of data from the US Women's Health Initiative shows.

Researchers studied 1,064 women with a mean age of 55.

For any value of diastolic blood pressure, the probability of coronary artery calcium increased with higher levels of systolic blood pressure, whereas for any given value of systolic blood pressure, the probability of any coronary artery calcium decreased with higher levels of diastolic blood pressure.

A pulse pressure of 55 mm Hg was associated with a 95% increased risk of any coronary artery calcium, while women with isolated systolic hypertension had a 73% increased risk of coronary artery calcium.

Hypertension 2008 15 September early online publication

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