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Reducing heart rate cuts CVD risks

By Nigel Praities

Reducing heart rate in patients with angina results can reduce major cardiovascular events by a quarter, say researchers.

Their international study in 11,000 angina patients found the use of the sinus node inhibitor ivabradine was associated with a 24% reduction in the risk of cardiovascular mortality, heart attack or heart failure.

The study is a sub-analysis of the BEAUTIFUL study presented at the European Society of Cardiology congress last year. This study showed a 34% increased risk of cardiovascular mortality in high-risk patients with an elevated heart rate.

This latest post-hoc data from patients with angina with a heart rate of 70 bpm or above – presented last weekend at the European Society of Cardiology in Barcelona, Spain – also showed a 59% reduction in the need for coronary revascularisation.

Presenting the data at the conference, Professor Roberto Ferrari, ESC president and professor of cardiology at the University of Ferrara, Italy, said the reduction in events was largely due to a reduction in hospitalisations for heart attack.

‘Ivabradine may be helpful to reduce major cardiovascular events in patients with angina. These results are plausible and in line with previous results with ivabradine,' he said.

The results have been published in full online in the European Heart Journal.

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