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Two-thirds of long-term gout patients 'not prescribed urate-lowering therapies'


I think there are arguments about how liberal we have been using uricosuric drugs(allopurinol , febuxostat ) in gout: (1) Gout is associated with higher CVD risk and metabolic syndrome. If these co-morbidities are already present, there may be a lower threshold to treat hyperuricaemia (2) Hyperuricaemia is commonly caused by diuretics ( both thiazide or loop diuretics ) (3) keeping the uric acid low enough (<300ug/l ) is essential and that really stops uric acid deposition . Perhaps this is the 'cure' they were talking about. (4)Of course , it is again risk of polypharmacy and patient may not like to take tablet everyday. That is exactly why we tailor the treatment in individual case.

Posted date

15 Jan 2014

Posted time