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'My mother died of bowel cancer, am I at risk too?' - managing Lynch syndrome


These are the early days of genetic oncology. I have no doubt that in the next few decades there will be an information explosion and many more "syndromes" will be named associated with genetic mutations. I came across this genetic report "No exonic copy number variants detected in APC, MLH1, MSH2, MSH6, PMS2 (exons 1-10), EPCAM, STK11, PTEN, SMAD4 or BMPR1A" for a 39 year old with Colonic Cancer. Unlikely Lynch syndrome then but (s)he has had counselling and the progeny will be screened at some point. (Please note even as anonymised, permission received to mention the above)

Posted date

23 Mar 2019

Posted time