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SSRIs cut PMS symptoms

SSRIs are effective in reducing the symptoms of severe premenstrual syndrome, according to a meta-analysis by US researchers.

Data from 29 trials including almost 3,000 women showed SSRIs are effective for reducing the symptoms of PMS and premenstrual dysphoric disorder, with the risk falling by 60% compared with placebo.

There was no significant difference between SSRIs studied and the effect of treatment, but continuous dosing seemed to give a better response than intermittent dosing.

Obstetrics and Gynecology 2008;111:1175-82

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