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Main Page Content:

Researchers recommend 'double-whammy' for smokers to increase quit rates

17 Dec 09

Smokers are more likely to quit if they are prescribed a combination of smoking cessation treatments, according to a large study in primary care.

The study – published in this week’s Archives of Internal Medicine – looked at 1,300 smokers attending appointments at primary care clinics and found the combination of bupropion and a nicotine lozenge was the most effective at helping them quit.

At six months, abstinence rates for bupropion plus nicotine lozenge treatment was 30%, and for nicotine patch plus lozenge was 27%.

Patients on monotherapy had significantly lower quit rates at six months - 17% for bupropion, 20% for nicotine lozenges and 18% for nicotine patches.

Lead author Professor Stevens Smith, associate professor of medicine at the University of Wisconsin in the US, said: ‘In this comparative effectiveness study of five tobacco dependence treatments, combination pharmacotherapy significantly increased abstinence compared with monotherapies.'

‘Provision of free cessation medications plus quit line counselling arranged in the primary care setting holds promise for assisting large numbers of smokers to quit.’

Readers' comments

  • JohnRPolito | 17 Dec 09

    Pulse missed the real story here, that regardless of group assignment, participants receiving greater than 90 minutes of telephone counseling generated a whopping 36% six-month cessation rate. In fact, the study's dual pharm product use findings are troubling. With nearly 40% of current nicotine gum users hooked on the cure, it is highly irresponsible to study and advocate dual NRT use while ignoring evaluation of chronic long-term chemical dependency upon NRT and/or bupropion. Neither this study or its companion clinical trial presents any evidence that any study participant actually broke nicotine's grip upon their mind and life. None. Imagine pronouncing those using multiple avenues to stimulate brain dopamine pathways as having been most successful, when blood, saliva and urine were not examined to determine if stimulation by quitting products actually ended. What percentage of this study's successful quitters remain hooked on nicotine lozenges today? We don't know. Does informed consent demand that smokers be warned of their odds of getting hooked on the cure? Absolutely! New Year's is by far the biggest quitting day of the year. I saw an older BBC survey showing that almost 90% of all long-term ex-smokers quit smoking cold turkey. At WhyQuit we've tried to build a counseling and support site that insulates quitters from pharm industry marketing tactics while teaching the keys to successful abrupt nicotine cessation. If you work for the NHS I hope you'll expore the site and consider referring cold turkey quitters to us. Still only one rule providing a 100% guarantee of success ... no nicotine today! John R. Polito - Nicotine Cessation Educator


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17 Dec 09

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