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TB drug resistance rises

Resistance to drugs for tuberculosis is rising sharply in England, Wales and Northern Ireland, a Health Protection Agency study reports.

The researchers analysed susceptibility data among a cohort of 28,620 tuberculosis cases dating from 1998 to 2005.

The proportion of cases resistant to isoniazid increased from 5% to 7%, and resistance to rifampicin increased marginally from 1.0% to 1.2%. Multi-drug resistance also increased marginally, from 0.8% to 0.9%.

BMJ 1 May early online publication

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