Tiotropium best at cutting COPD exacerbations
Tiotropium reduces the risk of exacerbations and hospitalisations compared with combined ipratropium/salbutamol in patients with COPD, a UK study concludes.
The researchers analysed data on 4,193 patients on the UK general practice research database, 3,385 of them on tiotropium and 808 of them on ipratropium/salbutamol.
After controlling for the severity of illness, treatment with tiotropium reduced the risk of an exacerbation by 26% and the risk of COPD-related referrals and hospitalisations by 43%.
Primary Care Respiratory Journal 2008 2 April early online publication