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Trans-fats in diet raises breast cancer risk

Women with diets high in trans-monounsaturated fatty acids face an increased risk of developing breast cancer, French researchers report.

Their cohort study looked at the relationship between serum phospholipid fatty acid levels and breast cancer risk in 19,934 women aged 40 to 60 years. They used biomarkers of dietary fatty acids as an objectively measure bioavailable nutrients.

Women in the highest quintile for serum levels of trans-monounsaturated fatty acids had a 1.75-fold increased risk of breast cancer compared with women in the lowest quintile.

Am J Epidemiol 2008; early online publication

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