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UKPDS team add in Framingham to create new risk tool

The research group that developed the risk engine modelled on the UK prospective diabetes study have created a new tool for use by GPs by combining it with the Framingham equation.

Although the NICE lipid modification draft guidance makes the Framingham equation a keystone of cardiovascular risk assessment, the equation is known to underestimate the higher CVD risks in people with type 2 diabetes.

The Oxford Risk Engine, presented at the American Diabetes Association annual meeting in Chicago, was developed by the Diabetes Trials Unit at the University of Oxford and designed 'for ease of use in everyday clinical practice'.

Using the Oxford Risk Engine, a 50-year-old, white, non-smoking, non-diabetic male with a blood pressure of 145/85mmHg, cholesterol of 5.2mM and HDL of 1.1mM has an estimated 10-year CVD risk of 13.8% – less than half the 24.2% risk estimated using UKPDS.

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