Cookie policy notice

By continuing to use this site you agree to our cookies policy below:
Since 26 May 2011, the law now states that cookies on websites can ony be used with your specific consent. Cookies allow us to ensure that you enjoy the best browsing experience.

This site is intended for health professionals only

At the heart of general practice since 1960

Insulin/liraglutide combo more effective than either alone

  • Print
  • Comment
  • Save

A combination injection of insulin and liraglutide significantly improves glycaemic control in type 2 diabetes compared with either drug alone, according to the results of a UK study.

The 26 week trial of 834 patients inadequately controlled with metformin and pioglitazone randomised patients to the fixed dose combination of insulin degludec and liraglutide, or each of the components as monotherapy.

At the start of the trial the average HbA1c was 67mmol/mol (8.3%) and this dropped by 21 mmol/mol (1.9%) to 46 mmol/mol (6.4%) with the combination, significantly greater than the drop of 15mmol/mol with insulin degludec and 14mmol/mol with liraglutide.

The study was sponsored by Novo Nordisk and presented at the European Association for the Study of Diabetes (EASD) 2013 Meeting in Barcelona.

Have your say

  • Print
  • Comment
  • Save