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Vitamin D depression link

Older adults with low blood levels of vitamin D and high serum parathyroid hormone may be at a high risk of depression, say Dutch researchers.

A study of more than 1,200 older people, aged 65-95, found vitamin D levels were 14% lower in those with depression than without the condition. Parathyroid hormone levels were an average of 5% higher in those with mild depression and 33% higher in those with major depression than in those who were not depressed.

Further research was needed to determine whether the changes preceded depression or followed it, the team concluded.

Archives of General Psychiatry 2008;65:508-12

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