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Weight gain speeds lung function decline in asthma patients

Gaining weight increases the rate of FEV1 decline in patients with asthma, according to the European Community Respiratory Health Survey.

Spirometry was performed on 638 patients aged 22-44 years old with asthma in 1991-1993 and again in 1998-2002.

A faster FEV1 decline was observed for patients with intermediate BMI compared to lean and already obese patients. The association was stronger in men for whom FEV1 declined by 20 ml/year for every kg gained compared to an FEV1 decline of 6 ml/year in women for every kg gained.

J Allergy & Clinical Immunology 2009; 123(5):1069-74.

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