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Why should I look beyond sugar in T2D management?

The FORXIGA® (Dapagliflozin) prescribing information is available via the tabs throughout the site. Adverse event reporting information can be found at the bottom of this page.

Why should I look beyond sugar in T2D management?

Approximately 3.4 million people in the UK live with T2D1 and most experience complications.2 60% of first complications are due to heart failure (HF) and chronic kidney disease (CKD) resulting from the simultaneous impact of T2D on the cardiovascular and renal organ systems.3 

Furthermore, compared with comorbidity-free patients with T2D, cardiorenal disease (HF or CKD) is associated with a greater risk of mortality than even stroke, peripheral arterial disease (PAD) and myocardial infarction (MI).3

In line with this, the complications associated with T2D place a significant burden on not only patients but also the NHS healthcare system, accounting for 80% of the NHS’ spend for the management of T2D.4

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Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to AstraZeneca by visiting https://aereporting.astrazeneca.com or by calling 0800 783 0033.

References

1. Diabetes.org.uk. Number of people with diabetes reached 4.7 million. https://www.diabetes.org.uk/about_us/news/new-stats-people-living-with-diabetes. Accessed September 2022.

2. Arnold SV, et al. Diabetes Obes Metab 2018;20:2000-2003.

3. Birkeland KI et al. Diabetes Obes Metab 2020;22:1607–1618.

4. Diabetes UK. The cost of diabetes report 2014. https://www.diabetes.org.uk/resources-s3/2017-11/diabetes%20uk%20cost%20of%20diabetes%20report.pdf. Accessed July 2022.

5. NHS. End of life care in heart failure. https://www.england.nhs.uk/improvement-hub/wp-content/uploads/sites/44/2017/11/heart-failure.pdf. Accessed August 2022.

6. Kidney Care UK. Facts and Stats. https://www.kidneycareuk.org/news-and-campaigns/facts-and-stats/ Accessed July 2022.