This site is intended for health professionals only

At the heart of general practice since 1960

Call for HPV vaccination to be extended to young gay men

Sexual health experts are calling for young gay men under the age of 26 years to receive the HPV vaccination, because they are at a high risk of developing anal cancer.

The team argues targeting young gay men would be cost effective even though a small proportion of young, identifying men who have sex with men (MSM) may already be infected with HPV 16 or 18, the two strains that account for most genital cancers.

Gay men have 15 times the risk of developing genital cancer, particularly anal cancer, as a result of HPV infection compared with straight men.

Writing in an editorial in the BMJ journal Sexually Transmitted Infections, the experts said that young gay men could be targeted through sexual health clinics, where they are already offered hepatitis B vaccination – and that this would also help to improve access to services for such men, who are also vulnerable to HIV infection.

They wrote: ‘While the biggest challenge will be to identify and vaccinate before HPV acquisition, recent data illustrates HPV vaccination of sexually active MSM is effective, and modelling using conservative analyses suggests vaccination is cost-effective.

‘In the light of this evidence, and in the absence of universal vaccination of boys, the argument for introducing targeted HPV vaccination or MSM up to age 26 years is strong.’

The call comes after a move by the BMA earlier this year urging ministers to widen the HPV vaccination programme to include gay men.

But GPs have expressed concerns over targeting young gay men for HPV immunisation, because of the difficulty of identifying them and getting them to come forward at such a young age.

Dr Catti Moss, RCGP advisor on sexual health and a GP in Northampton, said: ‘The practicalities of identifying those gay men before they have already picked up HPV would be very difficult. Many men are unsure of their orientation in early teens.’

Dr Moss said targeting this group could be done ‘in theory’ by a combination of sexual health and outreach clinics and general practice. But she said it would be more effective to vaccinate both sexes in their early teens – and that the current HPV programme run through schools could vaccinate boys equally as well as girls.

Dr Moss said: ‘If we wish to cut the impact of HPV on anal, cervical, penile, and other cancers really effectively, the best way is to immunise both sexes (together, in their early teens). This would have the good side effect that herd immunity would have a chance to build up.’

Sex Transm Infect 2013; 89: 342–343

Readers' comments (2)

  • This is a good idea, though not a new one.

    1. English PM. Who should be offered the HPV vaccine outside the planned programme? Vaccines in Practice 2008;1(1):1-4. (available via - free registration/login required)

    Unsuitable or offensive? Report this comment

  • arguably I understood the concept of leaving males out of the vaccination scheme as the purpose of the HPV vaccines was to reduce the cervical cancer. If the objective is to minimize all genital cancers in men and women, to leave out straight men is frankly discriminatory. The argument of anal cancer is understandable by virtue of cost effectiveness, however this conveniently has left out all the other skin and penile pathology associated in straight and gay men alike. I urge people stop wasting time in the debate and simply vaccinate every child male and female, and you minimize the problem.

    Unsuitable or offensive? Report this comment

Have your say