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Evidence ‘inconclusive’ for benefits of vitamin D in pregnancy, study finds


Vitamin D deficiency


The evidence for vitamin D reducing the likelihood of gestational diabetes and preeclampsia is ‘inconclusive’ according to a new study.

The study suggests that the evidence for recommending vitamin D supplements to pregnant women is weak and that supplementation may not reduce the risk of adverse outcomes in pregnancy.

The study, carried out by an international team of researchers, looked at just under 7,400 women using data from two European pregnancy studies. Researchers looked at their antenatal vitamin D levels and also looked at the genetic variations that the women had that were associated with vitamin D production.

They found no strong evidence of a causal association between vitamin D levels and gestational hypertension, and only weak evidence of an association between vitamin D levels and preeclampsia.

They also found no consistent evidence of an association between the genetic variations and gestational hypertension and preeclampsia.

The authors said in the paper: ‘According to the World Health Organization, evidence recommending vitamin D supplementation for women during pregnancy to reduce adverse pregnancy outcomes is insufficient.

‘Our findings support the current WHO position.’

NICE currently suggests that GPs recommend vitamin D supplements at first contacts with all pregnant women.

BMJ 2018; available 21st June