By Alisdair Stirling
Intensive lifestyle intervention can produce sustained weight loss and improvements in fitness, glycaemic control and CVD risk factors in patients with type 2 diabetes, a new study suggests.
US researchers compared the effects in 2,570 patients offered intensive lifestyle intervention - portion-control, a low-fat and high-protein diet modification, and at least 175 minutes of physical activity a week – and 2,575 controls who received diabetes support and education only.
Averaged across four years, patients in the intervention group had a 5% greater weight loss and greater improvements in treadmill fitness at 12.74% compared with 1.96%.
HbA1c level fell more in those with lifestyle interventions at 0.36% compared with 0.09%, as did systolic blood pressure at 5.33 compared with 2.97mm Hg and diastolic blood pressure, which fell by 2.92 compared with 2.48mm Hg. HDL-cholesterol also fell more, by 3.67% compared with 1.97%. Higher levels of all these markers were maintained in the treatment group after four years.
Study leader Dr Rena Wing, a researcher in psychiatry and human behaviour at Brown University said: ‘Intensive lifestyle intervention can produce improvements in CVD risk factors but whether these differences in risk factors translate into reduction in CVD events is unknown.'
Arch Intern Med 2010;170(17):1566-1575credit: maHidooi, flickr Intensive lifestyle advice 'improves fitness in diabetes patients'