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Covid-19 Primary Care Resources

How should GPs manage post-Covid depression and Chronic Fatigue?

Advice from a Consultant Neuropsychiatrist

This information is sourced from Dr Tim Nicholson, Consultant Neuropsychiatrist

Q. Should GPs expect to see Post-Covid depression / Chronic Fatigue symptoms and are some treatments more likely to be beneficial than others?


  • We are already starting to see such cases and we predict this will be a significant, and likely very significant, clinical problem in the coming months
  • We don’t have any evidence to suggest different treatment from routine / non-Covid-19 cases of depression and Chronic Fatigue Syndrome (CFS) so we’d recommend following NICE guidelines for CFS and depression
  • What will be critical with the CFS, or CFS-like, cases will be ensuring – as always – that the reality and severity of their symptoms are acknowledged and gradually paced rehabilitation is encouraged; psychosocial factors should not be assumed to be present but should be sensitively explored if thought relevant