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Covid-19 Primary Care Resources


PRINCIPLE Trial


Oxford vaccine


One of the largest Covid studies relevant to General Practice in the UK

This information is sourced from the Primary Care Clinical Trials Unit, University of Oxford:

Brief outline;

Led by the Primary Care Clinical Trials Unit at Oxford University. The Platform Randomised trial of Interventions against COVID-19 in older people (PRINCIPLE) trial will involve hundreds of GP practices.  It will test which pharmacological treatments are more effective at reducing morbidity in high risk patients with COVID-19,

Signing up

A representative from an interested practice should email the trial recruitment team:

principle@phc.ox.ac.uk Telephone 0800 138 0880

Questions the recruitment officer will ask:

1. Is the practice part of the RCGP Research and Surveillance Network? ( practice is still eligible if not)

2. Is the practice registered with ImmForm? (vaccine register)

3. Is there a GP lead who has completed the NIHR Good Clinical Practice training within the last 3 years, or is willing to complete the e-learning training (approx. 4 hours) or refresher (3 hours)?

4. Which clinical system does the practice use?

5. Is there a supply of swabs at the practice?

6. Is the practice active or willing to start sending self-swabs to patients?

Favipiravir, an antiviral drug used to treat flu has been added to the PRINCIPLE trial